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4-[(1S,2S,5S,9R)-5-(hydroxymethyl)-8,9-dimethyl-3-oxabicyclo[3.3.1]non-7-en-2-yl]phenol

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule with the formula C17H24O3 and a molecular weight of approximately 276 g/mol[1][2][5]. It is listed as an experimental pharmaceutical in chemical databases and has been identified as a potential endocrine-disrupting compound[1]. Structural studies indicate it can bind to nuclear hormone receptors such as the estrogen receptor alpha ligand-binding domain (as seen in PDB structure complexes), suggesting it may act as a modulator of steroid hormone signaling pathways[6]. However its clinical development status and therapeutic indications are not established; it remains primarily an experimental or research tool.

Other names
4-[(1R,2S,5S,8S,9R)-5-(hydroxymethyl)-8,9-dimethyl-3-oxabicyclo[3.3.1]nonan-2-yl]phenol4-((1R,2S,5S,8S,9R)-5-(hydroxymethyl)-8,9-dimethyl-3-oxabicyclo(3.3.1)nonan-2-yl)phenol4[((1S,2S,5S,9R))-5-(hydroxymethyl)-8,9-dimethyl]-3-Oxabicyclo[3.3.1]nonan–7-en–2–yl phenol
02

Targets

ESR1 (ERα)

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